Doctors usually categorize leukemia into four main types based on the type of blood cells it affects: acute lymphoblastic leukemia (ALL) acute myeloid leukemia (AML) chronic lymphocytic leukemia (CLL)
Unlike acute myeloid leukemia (AML), CML takes longer to develop. Most people can live with CML for many years. Rarely CML can also turn into acute leukemia, which needs immediate medical attention.
AML and ALL are both cancers of the blood and bone marrow. The main difference between the two is that AML affects the production of myeloblasts, red blood cells, and platelets, whereas ALL mainly affects the production of lymphocytes.
Chronic lymphocytic leukemia (CLL) starts in bone marrow, the soft inner part of your bones. There are some key differences that set CLL apart from other types of leukemia, such as ALL (acute lymphocytic leukemia), AML (acute myeloid leukemia), and CML (chronic myeloid leukemia).
AML progresses rapidly and involves white blood cells that aren't fully developed, called blasts. CML progresses more slowly and involves blood cells that are more mature.
CLL is like ALL, but it's chronic instead of acute, meaning that it's more slow-growing and takes longer to start causing symptoms. When CLL does cause symptoms, these may include swelling in the lymph nodes (neck, underarm, stomach or groin), fatigue, fever, infection, weight loss and more.
Stage 4 – A patient has high levels of white blood cells and low platelets. He or she may also be anemic, have enlarged lymph nodes and have an enlarged liver or spleen.
So one way to obtain a clue is to look at the mature cells. If most of the mature cells seen are lymphocytes, then it could possibly be ALL. If neutrophils or other cells in the myeloid line are seen, then it is more likely to be an AML. One clue that is almost foolproof is the presence of Auer Rods.
It uses stage groupings that have a value of 0 or 1 through 4 using Roman numerals I, II, III, and IV. The higher the number, the more advanced the cancer is. The Rai system then groups CLL into low (stage 0), intermediate (stages I and II), and high (stages III and IV) risk groups.
Leukemia is a blood cancer that develops in early blood-forming cells. There are four main types of leukemia – acute myeloid leukemia (AML), chronic myeloid leukemia (CML), acute lymphoblastic leukemia (ALL) and chronic lymphocytic leukemia (CLL).
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